Per-vial pricing. 10-vial lot. For research use only. Not for human consumption.

Per-vial pricing. 10-vial lot. For research use only. Not for human consumption.

Per-vial pricing. 10-vial lot. For research use only. Not for human consumption.

Per-vial pricing. 10-vial lot. For research use only. Not for human consumption.

Per-vial pricing. 10-vial lot. For research use only. Not for human consumption.

Per-vial pricing. 10-vial lot. For research use only. Not for human consumption.

Identity
CAS: 53-84-9
Molecular formula: C21H27N7O14P2
Purity: ≥99% (HPLC)
Form: sterile lyophilised powder
Presentation: 3 mL vial

Research literature
Research on nicotinamide adenine dinucleotide (NAD+) and its precursors investigates a coenzyme central to redox reactions, sirtuin signalling, and mitochondrial function. Animal-model work in aged mice characterises the effects of NAD+ repletion via nicotinamide riboside on mitochondrial unfolded-protein response, muscle stem-cell function, and lifespan distribution. Long-term studies in mice further examine oral nicotinamide mononucleotide administration in the context of age-associated physiological decline, energy metabolism, and insulin sensitivity.

References

1. Zhang H et al. (2016). NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice. Science. PMID 27127236.
2. Mills KF et al. (2016). Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice. Cell Metabolism. PMID 28068222.

Documentation
Batch Certificate of Analysis (HPLC, third-party) provided for the lot shipped.

Handling (research)
Store lyophilised cold and protected from light. Reconstitute according to the researcher’s own laboratory procedure.

For Research Use Only. Not for Human or Veterinary Use. Not a drug, food, or supplement; not evaluated by the FDA; not intended for human or animal use.

Identity
Sequence: Lys-Pro-Val (KPV)
CAS: 67727-97-3
Molecular formula: C16H30N4O4
Purity: ≥99% (HPLC)
Form: sterile lyophilised powder
Presentation: 3 mL vial

Research literature
Research on KPV (Lys-Pro-Val) investigates the C-terminal tripeptide fragment of α-melanocyte-stimulating hormone. In-vitro studies characterise its inhibition of NF-κB activation and pro-inflammatory cytokine signalling, and in-vivo work in murine colitis models examines its uptake via the PepT1 di/tripeptide transporter and effects on intestinal inflammation in DSS- and TNBS-induced disease. Subsequent animal studies further investigate the PepT1/KPV axis in the context of colitis-associated tumour development.

References

1. Dalmasso G et al. (2008). PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation. Gastroenterology. PMID 18061177.
2. Viennois E et al. (2016). Critical role of PepT1 in promoting colitis-associated cancer and therapeutic benefits of the anti-inflammatory PepT1-mediated tripeptide KPV in a murine model. Cellular and Molecular Gastroenterology and Hepatology. PMID 27458604.

Documentation
Batch Certificate of Analysis (HPLC, third-party) provided for the lot shipped.

Handling (research)
Store lyophilised cold and protected from light. Reconstitute according to the researcher’s own laboratory procedure.

For Research Use Only. Not for Human or Veterinary Use. Not a drug, food, or supplement; not evaluated by the FDA; not intended for human or animal use.

Identity
Sequence: Gly-His-Lys (GHK), copper(II) complex
CAS: 89030-95-5 (Cu complex); 49557-75-7 (free GHK)
Molecular formula: C14H22CuN6O4 (GHK-Cu)
Purity: ≥99% (HPLC)
Form: sterile lyophilised powder
Presentation: 3 mL vial

Research literature
Research on GHK-Cu investigates a copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine, a sequence present in human plasma and in collagen. In-vitro studies in dermal-fibroblast cultures characterise its stimulation of collagen and glycosaminoglycan synthesis at picomolar-to-nanomolar concentrations. Gene-expression analyses in human cell systems further examine the tripeptide-copper complex’s modulation of pathways related to tissue remodelling, antioxidant defence, and extracellular-matrix turnover.

References

1. Maquart FX et al. (1988). Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. FEBS Letters. PMID 3169264.
2. Pickart L, Margolina A (2018). Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. International Journal of Molecular Sciences. PMID 29986520.

Documentation
Batch Certificate of Analysis (HPLC, third-party) provided for the lot shipped.

Handling (research)
Store lyophilised cold and protected from light. Reconstitute according to the researcher’s own laboratory procedure.

For Research Use Only. Not for Human or Veterinary Use. Not a drug, food, or supplement; not evaluated by the FDA; not intended for human or animal use.

• CJC-1295 no DAC 10mg — Modified GRF(1-29), no DAC.
• Ipamorelin 10mg — Pentapeptide GH secretagogue.

Identity
Purity: ≥99% (HPLC)
Form: sterile lyophilised powder
Presentation: 3 mL vial

Research literature
This blend combines modified GRF(1-29) — the no-DAC CJC-1295 species — with ipamorelin, a selective pentapeptide growth-hormone secretagogue. Foundational research on the CJC-1295 albumin-conjugate platform in rat anterior pituitary cells investigates GRF-receptor activation and in-vitro stability, while research on ipamorelin in rat pituitary cultures and pentobarbital-anaesthetised rats characterises its potency and selectivity at the GHS-R1a receptor relative to GHRP-6. The two peptides are studied as complementary research tools for examining somatotroph signalling.

References

1. Jetté L et al. (2005). Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog. Endocrinology. PMID 15817669.
2. Raun K et al. (1998). Ipamorelin, the first selective growth hormone secretagogue. European Journal of Endocrinology. PMID 9849822.

Documentation
Batch Certificate of Analysis (HPLC, third-party) provided for the lot shipped.

Handling (research)
Store lyophilised cold and protected from light. Reconstitute according to the researcher’s own laboratory procedure.

For Research Use Only. Not for Human or Veterinary Use. Not a drug, food, or supplement; not evaluated by the FDA; not intended for human or animal use.